THE SEROLOGICAL AND MOLECULAR-BIOLOGICAL MARKERS OF CYTOMEGALOVIRUS INFECTION IN WOMEN IN BAKU CITY
Abstract
At present time the problem of cytomegalovirus infection (CMVI) has a high interest. The necessity of studying of CMVI have been called with their widley spreading and with those that cytomegalovirus is able to caused the different in ne wborns and children, whose mothers have been sicked with CMVI during pregnancy.
The aim of investigation is to study the seroepidemiological pecularities of CMVI in women in Baku city.
With according in 2018 year on the base of the clinical epidemiology laboratory of Azerbaijan Medical University the patients for CMVI have been observed. The middle age of women were 42,5±2,7 years old.
In order to laboratory diagnostic of CMVI the immunosorbent assay method (IFA) and the polymerase chain reaction (PCR) have been used.
It was determined that from 173 patients with pozitiv CMV antigen the 45 has the gynecological pathologies (26,0%).
At women an acute cytomegalovirus infection have been diagnosed in 26,0% of cases and most appearance have been detected in the age group 40-49 (28,6%). The cytomegalovirus infection at women have been appeared in association with HSV I (2,9%) and HSV II (5,2%) types of cases in acute, latent and reactivated forms.
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Список литературы
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Leruez-Ville M., Selier Y., Salomon L. et al. Prediction of fetal infection in cases with cytomegalovirus immunoglobulin M in the first trimestr of pregnancy: a retrospective cohort. Clin. Infect. Dis., 2013, vol. 56(10), pp. 1428-1435.
Luvira V., Chamnanchanunt S., Bussaratid V. et al. Seroprevalence of latent cytomegalovirus infection among elderly Thais. Southeast Asian J. Trop. Med. Publ. Hlth., 2012, vol. 43(6), pp. 1419-1425.
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Schampera M., Schweinzer K., Abele H. et al. Comparison of cytomegalovirus – specific neutralization capacity of hyperimmunoglobulin versus standart intravenous immunoglobulin preparations: impact of CMV IgG normalization. J. Clin. Virol., 2017, vol. 90, pp. 40-45.
Sellier Y., Guilleminot T., Ville Y. et al. Comparison of the LIAISON CMV IgG Avidity II and the VIDAS CMV IgG Avidity VV assays for the diagnosis of primary infection in pregnant women. J. Clin. Virol., 2015, pp. 46-48.
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