The relationship between arterial hypertension and long COVID

Keywords: postcovoid syndrome, long COVID, arterial hypertension, coronavirus infection

Abstract

Background. Рost-COVID-19 syndrome (long COVID) is the signs and symptoms that develop during or after COVID-19 infection that last for more than 12 weeks and are not explained by an alternative diagnosis. 

Purpose. To identify the features of the course of long COVID in patients with arterial hypertension.

Materials and methods. A study was conducted with 104 patients (mean age 49.5±6.4 years) hospitalized due to viral pneumonia caused by COVID-19. Group 1 included 49 patients with arterial hypertension (AH) (47.1%), group 2 – 55 patients without AH (52.9%).  The patient's condition was assessed during hospitalization, before discharge, 1-2 days after discharge, and then remotely after 3, 6, and 12 months. In addition to routine methods, the prevalence of various symptoms characteristic of long COVID was studied. The assessment of well-being was carried out on a 10–point scale, where 1 point – "very bad", 10 points - "excellent".

The statistical analysis was performed using the StatTech v program. 4.6.3 (developed by Stattech LLC, Russia).

Results. The presence of hypertension negatively affects the course of long COVID in the form of a deterioration in general well-being compared to the state before coronavirus infection. In group 1, the well-being index at the first visit after discharge from the hospital was lower than in group 2 (7 [6.98;7.03] and 8 [7.96;8.01], respectively, p=0.008). The absence of hypertension had a positive effect on the dynamics of myalgia and glucose levels in the postcovoid period (p<0.05).

Conclusion. Thus, the presence of hypertension in patients with coronavirus infection complicated by pneumonia entails the persistence of postcovoid symptoms. Therefore, they need regular dynamic monitoring for at least a year after suffering from COVID-19.

EDN: UZIPRB

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Author Biographies

Liutsiia I. Feiskhanova, Kazan State Medical University of the Ministry of Health of the Russian Federation

MD, Associate Professor of the Department of Hospital Therapy

Ekaterina E. Petrova, Kazan State Medical University of the Ministry of Health of the Russian Federation

Student

Zulfiya F. Kim, Kazan State Medical University of the Ministry of Health of the Russian Federation

MD, Associate Professor of the Department of Internal Medicine

Stanislav Yu. Scherbakov, Kazan State Medical University of the Ministry of Health of the Russian Federation

Assistant of the Department of Anesthesiology and Resuscitation

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Published
2025-12-30
How to Cite
Feiskhanova, L., Petrova, E., Kim, Z., & Scherbakov, S. (2025). The relationship between arterial hypertension and long COVID. Siberian Journal of Life Sciences and Agriculture, 17(6-1), 432-444. https://doi.org/10.12731/2658-6649-2025-17-6-1-1353
Section
Public Health and Preventive Medicine