METABOLIC SYNDROME: ASSESSMENT OF QUALITY OF LIFE, ANXIETY AND DEPRESSION IN PATIENTS
Abstract
Rationale. The article examines the assessment of the quality of life, psychological state (anxiety-depressive disorders, neurosis-like states) in patients with metabolic syndrome. The prevalence of metabolic syndrome in different countries is 25-30% and varies depending on the criteria used. The severity of the clinical manifestations of the metabolic syndrome affects the quality of life of patients, while the indicators of physical and mental health decrease. The problem of the quality of life of patients suffering from overweight and obesity is relevant and socially significant. Obesity leads to anxiety-depressive disorders, neurosis-like states, which contributes to a worsening of the prognosis of the underlying disease. The number of patients with chronic metabolic disorders (obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease) is increasing in the world every year.
The aim of our work was to assess the quality of life, the level of anxiety and depression in patients with metabolic syndrome.
Materials and methods. The authors presented the results of a study of 60 patients with metabolic syndrome and 45 apparently healthy volunteers. Examination of patients, determination of anthropometric indicators with an assessment of the quality of life (questionnaire SF-36) were carried out. The level of anxiety and depression was determined according to the hospital scale of anxiety and depression HADS. Statistical processing of the obtained data was carried out using the application package "STATISTICA 8.0".
Results. Most of the quality of life indicators were statistically significantly different in patients with metabolic syndrome relative to the control group. There was a decrease in the average level of the parameters "physical functioning" by 17.3%, "role functioning" by 31%, "general health" by 11.3%, "vitality" by 13%, "emotional functioning" by 50.1%. ... The level of anxiety and depression in patients with metabolic syndrome corresponded to the subclinical level, the level of depression exceeded the value of the control group by 18%.
Conclusion. The study shows that patients with metabolic syndrome are characterized by a decrease in quality of life indicators, subclinically severe anxiety / depression. The goal of any treatment, according to MAPI Research Institute specialists, is to improve the quality of life of patients to the level of healthy individuals, therefore, for patients with metabolic syndrome, along with pathogenetic therapy aimed at reducing body weight, correction of psychological disorders is required, which will reduce the level of anxiety-depressive disorders and will improve quality of life indicators.
Downloads
References
Bespalova I.D., Medyantsev Yu.A., Kalyuzhin V.V. i dr. Kachestvo zhizni bol'nykh gipertonicheskoy bolezn'yu s metabolicheskim sindromom [Quality of life of patients with essential hypertension with metabolic syndrome]. Arterial'naya gipertenziya [Arterial hypertension], 2012, vol. 18, no. 4, pp. 304-309.
Vlasova O.L. Kliniko-psikhologicheskie osobennosti bol'nykh s razlichnymi proyavleniyami metabolicheskogo sindroma [Clinical and psychological characteristics of patients with various manifestations of the metabolic syndrome]. Smolensk, 2010, 26 p.
Derevyannykh E.V., Balashova N.A., Yaskevich R.A., Moskalenko O.L. Chastota i vyrazhennost' trevozhno-depressivnykh narusheniy u studentov meditsinskogo vuza [The frequency and severity of anxiety-depressive disorders in medical students]. V mire nauchnykh otkrytiy [In the world of scientific discovery], 2017, vol. 9, no. 1, pp. 10-28. https://doi.org/10.12731/wsd-2017-1-10-28
Derevyannykh E.V., Yaskevich R.A., Balashova N.A., Moskalenko O.L. Rasprostranennost' izbytochnoy massy tela sredi zhenshchin meditsinskikh rabotnikov krupnoy klinicheskoy bol'nitsy goroda Krasnoyarska [The prevalence of overweight among women medical workers of a large clinical hospital in the city of Krasnoyarsk]. V mire nauchnykh otkrytiy [In the world of scientific discovery], 2016, no. 7 (79), pp. 26-46. https://doi.org/10.12731/wsd-2016-7-2
Dzherieva I.S., Volkova N.I., Rapoport S.I. Assotsiatsiya mezhdu depressiey i metabolicheskim sindromom [Association between depression and metabolic syndrome]. Klinicheskaya meditsina [Clinical medicine], 2015, no. 1, pp. 62-65.
Dolganova N.P., Rotar' O.P. Kachestvo zhizni i osobennosti emotsional'nogo statusa u lits s riskom metabolicheskogo sindroma [Quality of life and features of emotional status in persons at risk of metabolic syndrome]. Klinicheskaya i meditsinskaya psikhologiya: issledovaniya, obuchenie, praktika [Clinical and Medical Psychology: Research, Training, Practice], 2014, no. 1(3). http://www.medpsy.ru/climp/2014_1_3/article04.php
Durneva M.Yu. Klinicheskaya i spetsial'naya psikhologiya [Clinical and special psychology], 2015, vol. 4, no. 3, pp. 1-19. https://doi.org/10.17759/psyclin.2015040301
Zavrazhnykh L.A., Smirnova E.N. Znachenie psikhologicheskikh kharakteristik patsienta dlya effektivnogo lecheniya metabolicheskogo sindroma [The importance of the psychological characteristics of the patient for the effective treatment of metabolic syndrome]. Klinitsist [Clinician], 2011, no. 3, pp. 49-55.
Metabolicheskiy sindrom [Metabolic syndrome]. ed. V. Fonseki. M.: «Praktika», 2011, 272 p.
Meshkova T.A. Rol' nasledstvennosti i sredy v etiologii narusheniy pishchevogo povedeniya. I. Obzor semeynykh issledovaniy [The role of heredity and environment in the etiology of eating disorders. I. Review of family studies]. Klinicheskaya i spetsial'naya psikhologiya [Clinical and special psychology], 2015, vol. 4, no. 1. http://psyjournals.ru/psyclin/2015/n1/Meshkova.shtml
Sergeeva L.S. Vliyanie osobennostey vospriyatiya bolezni na kachestvo zhizni patsientov s metabolicheskim sindromom [The influence of the characteristics of the perception of the disease on the quality of life of patients with metabolic syndrome]. Vestnik psikhoterapii: nauchno-prakticheskiy zhurnal [Psychotherapy Bulletin: scientific and practical journal], 2007, no. 20, pp. 81-88.
Sultanova A.S., Ivanova I.A. K probleme normativnykh pokazateley v patopsikhologicheskoy diagnostike [On the problem of normative indicators in pathopsychological diagnostics] [Elektronnyy resurs]. Klinicheskaya i spetsial'naya psikhologiya [Clinical and special psychology], 2017, vol. 6, no. 2, pp. 83-96. https://doi.org/10.17759/psyclin.2017060207
Tepaeva A.I. Kachestvo zhizni patsientov stradayushchikh izbytochnym vesom i ozhirenie rezul'taty sotsiologicheskogo analiza [The quality of life of patients suffering from overweight and obesity results of a sociological analysis]. Byulleten' meditsinskikh Internet - konferentsiy [Bulletin of medical Internet - conferences], 2013, vol. 3, no. 7, pp. 1027-1030.
Khokhlov A.L., Zhilina A.N., Buydina T.A. Vzaimosvyaz' pokazateley kachestva zhizni i osobennostey psikhologicheskogo statusa s klinicheskimi proyavleniyami metabolicheskogo sindroma [nterrelation of indicators of quality of life and characteristics of psychological status with clinical manifestations of metabolic syndrome]. Kachestvennaya klinicheskaya praktika [Good clinical practice], 2006, no. 2, pp. 19-23.
Yaskevich R.A., Moskalenko O.L. Antropometricheskie osobennosti i komponentnyy sostav massy tela u muzhchin migrantov kraynego severa s arterial'noy gipertoniey [Anthropometric features and component composition of body weight in male migrants from the Far North with arterial hypertension]. V mire nauchnykh otkrytiy [In the world of scientific discovery]. 2016. no. 10 (82), pp. 10-34.
Yaskevich R.A., Moskalenko O.L. Osobennosti variantov remodelirovaniya levogo zheludochka u muzhchin migrantov kraynego severa s arterial'noy gipertoniey, razlichnykh konstitutsional'nykh tipov [Features of variants of left ventricular remodeling in male migrants of the Far North with arterial hypertension, various constitutional types]. Siberian Journal of Life Sciences and Agriculture, 2020, vol. 12, no. 5, pp. 150-164. https://doi.org/10.12731/2658-6649-2020-12-5-150-164
Brunner E.J., Hemingway H., Walker B.R., Page M., Clarke P., Juneja M., Shipley M.J., Kumari M., Andrew R., Seckl J.R., Papadopoulos A., Checkley S., Rumley A., Lowe G.D., Stansfeld S.A., Marmot M.G. Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. Circulation, 2002, vol. 106, no. 21, pp. 2659-2665. https://doi.org/10.1161/01.cir.0000038364.26310.bd
Lakka H.M., Laaksonen D.E., Lakka T.A., Niskanen L.K., Kumpusalo E., Tuomilehto J., Salonen J.T. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA, 2002, vol. 288, no. 21, pp. 2709-2716. https://doi.org/10.1001/jama.288.21.2709
Lopez-Suarez A., Bascunana-Quirell A., Beltran-Robles M., Elvira-Gonzalez J., Fernandez-Palacin F., Barroso-Casamitjana E., Solino-Ocana I. Metabolic syndrome does not improve the prediction of 5-year cardiovascular disease and total mortality over standard risk markers. Prospective population based study. Medicine (Baltimore), 2014, vol. 93, no. 27, e212. https://doi.org/10.1097/MD.0000000000000212
Schutz Y. Macronutrients and energy balance in obecity. Metabolism, 1995, vol. 44, iss. 9, pp. 7‐11. https://doi.org/10.1016/0026-0495(95)90311-9
Scuteri A., Laurent S., Cucca F., Cockcroft J., Cunha P.G., Manas L.R., Mattace Raso F.U., Muiesan M.L., Ryliskyte L., Rietzschel E., Strait J., Vlachopoulos C., Volzke H., Lakatta E.G., Nilsson P.M., Metabolic S., Arteries Research C. Metabolic syndrome across Europe: different clusters of risk factors. Eur J. Prev Cardiol., 2015, vol. 22, no. 4, pp. 486-491. https://doi.org/10.1177/2047487314525529
Seppälä J. Depressive Symptoms, Metabolic Syndrome and Diet. Kuopio: University of Eastern Finland, 2012, 65 p.
Shurkevich N. P., Vetoshkin A. S., Gapon L. I., Gubin D. G. Structural changes in myocardium and 24-hour blood pressure profile in subjects with arterial hypertension studies during shift work in far north. European Heart Journal, 2018, vol. 39, s 1, pp. 596.
Stuckey M.I., Tulppo M.P., Kiviniemi A.M., Petrella R.J. Heart rate variability and the metabolic syndrome: a systematic review of the literature. Diabetes Metab Res Rev., 2014, vol. 30, no. 8, pp. 784-793. https://doi.org/10.1002/dmrr.2555
Tang F., Wang G., Lian Y. Association between anxiety and metabolic syndrome: A systematic review and meta-analysis of epidemiological studies. Psychoneuroendocrinology, 2017, vol. 77, no. 2, pp. 112-121. https://doi.org/10.1016/j.psyneuen.2016.11.025
Tuula H., Heiskanen L.K., Niskanen J.J. et al. Metabolic Syndrome and Depression: A cross-sectional Analysis. J. Clin Psychiatry, 2006, no. 67, pp. 1422-1427. https://doi.org/10.4088/jcp.v67n0913
Ware J.E., Kosinski M., Keller S.D. SF-36 Physical and Mental Health Summary Scales: A User`s Manual. The Health Institute. New England Medical Center. Boston, Mass. 1994.
Williams B., Mancia G., Spiering W. et al; ESC Scientific Document Group. 2018 ESC/ESH Guidelines for the management of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). European Heart Journal, 2018, vol. 39, no. 33, pp. 3021-104. https://doi.org/10.1093/eurheartj/ehy339
Yaskevich R.A., Moskalenko O.L. Analysis of the incidence and structure of the cardiovascular system diseases in the far north migrants over the period of readaptation to the new climatic conditions. In the world of scientific discovery, 2017, vol. 9, no. 4-2, pp. 59-73. https://doi.org/10.12731/wsd-2017-4-2-59-73
Yaskevich R.A., Moskalenko O.L. Anthropometric characteristics and component composition of body weight in male migrants of the far north with arterial hypertension. In the world of scientific discovery, 2017, vol. 9, no. 4, pp. 47-63.
Copyright (c) 2021 Olga L. Moskalenko, Olga V. Smirnova, Eduard V. Kasparov, Irina E. Kasparova
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
